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. Author manuscript; available in PMC: 2016 Mar 21.
Published in final edited form as: J Comp Neurol. 2013 Oct 15;521(15):3508–3523. doi: 10.1002/cne.23367

Figure 2.

Figure 2

Behavioral assessment of young and aged male Long-Evans rats in the spatial water maze. A: Cumulative search error across five blocks of training trials using a measure of proximity to the escape platform throughout the search. This assessment revealed impairment in spatial learning in aged rats relative to young; however, search on the initial learning trial was equivalent between the two groups. B: Memory index score of spatial bias during probe trial swimming. This measure reflects the average proximity to the escape platform location (platform retracted) across interpolated probe trials. Lower scores represent a more accurate search and better memory function than higher scores. As a group aged rats exhibited memory impairment on this task, but some aged rats performed within the normative range of the young and were characterized as aged unimpaired (AU). Those rats performing outside the range of young animals were characterized as aged impaired (AI). Error bars represent ± SEM.