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. Author manuscript; available in PMC: 2016 Mar 21.
Published in final edited form as: J Comp Neurol. 2013 Oct 15;521(15):3508–3523. doi: 10.1002/cne.23367

Figure 4.

Figure 4

GAD67-positive interneuron counts in hippocampal subfields CA1, CA3, and DG. A,B: Number of CA1 GAD67-positive neurons remains stable across the adult rat life span regardless of cognitive status. C,D: GAD67-positive neurons are reduced in AU and AI rats in the CA3 hippocampal subregion. E,F: GAD67-positive neurons are reduced in AU and AI rats in the DG moleculare (ML) and granule cell (GC) layers. Numbers of GAD67-positive neurons in the dentate hilus are depicted in Figure 5A,B. Error bars represent ± SEM. Y, young; AU, aged unimpaired; AI, aged impaired; GAD67, glutamic acid decarboxylase-67; SP, stratum pyramidal; SR, stratum radiatum; SO, stratum oriens; SLM, stratum lacunosum-moleculare. *P < 0.05.