Table 3.
Age-adjusted incidence rates*, incidence rate ratios (IRRs), and 95% confidence intervals (CIs), of classical Hodgkin lymphoma and selected histologic subtypes, by ethnic enclave tertile, Asians/Pacific Islanders (API), California, 1988-1992/1998-2002
| Characteristics | API Enclave§ | All classical Hodgkin lymphoma | Nodular sclerosis | Mixed cellularity | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N = 348 | N = 218 | N = 67 | ||||||||
| N | Rate* (95% CI) | IRR (95% CI) | N | Rate* (95% CI) | IRR (95% CI) | N | Rate* (95% CI) | IRR (95% CI) | ||
| ALL COMBINED | ||||||||||
| More ethnic | 158 | 0.87 (0.73-1.02) | 1.00 (reference) | 106 | 0.55 (0.45-0.67) | 1.00 (reference) | 24 | 0.16 (0.10-0.24) | 1.00 (reference) | |
| Intermediate | 77 | 1.12 (0.87-1.42) | 1.29 (0.95-1.74) | 52 | 0.71 (0.52-0.95) | 1.30 (0.89-1.86) | 13 | 0.21 (0.11-0.37) | 1.35 (0.62-2.85) | |
| Less ethnic | 113 | 1.69 (1.37-2.05) | 1.95 (1.50-2.52) | 60 | 0.83 (0.62-1.08) | 1.51 (1.06-2.11) | 30 | 0.50 (0.33-0.73) | 3.23 (1.77-5.95) | |
| SEX | ||||||||||
| Male | More ethnic | 95 | 1.11 (0.89-1.37) | 1.00 (reference) | 54 | 0.59 (0.44-0.78) | 1.00 (reference) | 17 | 0.22 (0.13-0.36) | 1.00 (reference) |
| Intermediate | 47 | 1.57 (1.13-2.14) | 1.42 (0.95-2.08) | 25 | 0.76 (0.47-1.16) | 1.28 (0.73-2.17) | 12 | 0.44 (0.22-0.78) | 1.95 (0.82-4.45) | |
| Less ethnic | 49 | 1.59 (1.15-2.14) | 1.43 (0.97-2.09) | 23 | 0.68 (0.41-1.05) | 1.15 (0.64-1.97) | 18 | 0.62 (0.35-1.00) | 2.75 (1.28-5.85) | |
| Female | More ethnic | 63 | 0.65 (0.50-0.84) | 1.00 (reference) | 52 | 0.52 (0.39-0.68) | 1.00 (reference) | 7 | 0.09 (0.04-0.20) | 1.00 (reference) |
| Intermediate | 30 | 0.75 (0.49-1.10) | 1.14 (0.70-1.84) | 27 | 0.68 (0.43-1.01) | 1.30 (0.77-2.17) | -- | -- | -- | |
| Less ethnic | 64 | 1.80 (1.37-2.33) | 2.75 (1.88-4.02) | 37 | 0.97 (0.68-1.36) | 1.88 (1.18-2.96) | 12 | 0.41 (0.21-0.73) | 4.42 (1.55-14.06) | |
| AGE GROUP AT DIAGNOSIS | ||||||||||
| 00-14 years | More ethnic | 11 | 0.29 (0.15-0.52) | 1.00 (reference) | 8 | 0.21 (0.09-0.42) | 1.00 (reference) | -- | -- | -- |
| Intermediate | 10 | 0.68 (0.33-1.25) | 2.32 (0.88-6.00) | 9 | 0.61 (0.28-1.16) | 2.86 (0.98-8.52) | -- | -- | -- | |
| Less ethnic | 5 | 0.33 (0.11-0.76) | 1.11 (0.30-3.48) | 5 | 0.33 (0.11-0.76) | 1.53 (0.40-5.31) | -- | -- | -- | |
| 15-39 years | More ethnic | 93 | 1.22 (0.98-1.49) | 1.00 (reference) | 73 | 0.96 (0.75-1.21) | 1.00 (reference) | 7 | 0.09 (0.04-0.19) | 1.00 (reference) |
| Intermediate | 42 | 1.35 (0.97-1.83) | 1.11 (0.75-1.62) | 33 | 1.07 (0.73-1.50) | 1.11 (0.71-1.70) | 3 | 0.10 (0.02-0.28) | 1.08 (0.18-4.77) | |
| Less ethnic | 54 | 1.76 (1.32-2.30) | 1.45 (1.01-2.05) | 35 | 1.15 (0.80-1.60) | 1.20 (0.78-1.82) | 11 | 0.35 (0.17-0.62) | 3.90 (1.37-11.92) | |
| 40-54 years | More ethnic | 21 | 0.60 (0.37-0.92) | 1.00 (reference) | 13 | 0.38 (0.20-0.64) | 1.00 (reference) | -- | -- | -- |
| Intermediate | 8 | 0.55 (0.24-1.09) | 0.91 (0.35-2.15) | -- | -- | -- | -- | -- | -- | |
| Less ethnic | 16 | 1.03 (0.59-1.68) | 1.71 (0.83-3.44) | 9 | 0.57 (0.26-1.08) | 1.51 (0.57-3.84) | -- | -- | -- | |
| 55+ years | More ethnic | 33 | 1.13 (0.77-1.61) | 1.00 (reference) | 12 | 0.38 (0.19-0.68) | 1.00 (reference) | 12 | 0.44 (0.22-0.78) | 1.00 (reference) |
| Intermediate | 17 | 1.75 (0.99-2.86) | 1.55 (0.79-2.93) | 6 | 0.67 (0.22-1.51) | 1.77 (0.49-5.25) | 6 | 0.55 (0.20-1.24) | 1.25 (0.38-3.78) | |
| Less ethnic | 38 | 3.60 (2.51-5.01) | 3.19 (1.91-5.34) | 11 | 1.05 (0.50-1.93) | 2.78 (1.05-7.06) | 17 | 1.65 (0.94-2.67) | 3.75 (1.64-8.88) | |
| NEIGHBORHOOD SES | ||||||||||
| Low | More ethnic | 38 | 0.88 (0.62-1.21) | 1.00 (reference) | 19 | 0.42 (0.25-0.66) | 1.00 (reference) | 9 | 0.21 (0.09-0.39) | 1.00 (reference) |
| Intermediate | 15 | 0.99 (0.55-1.66) | 1.13 (0.57-2.14) | 11 | 0.66 (0.33-1.21) | 1.58 (0.67-3.59) | -- | -- | -- | |
| Less ethnic | 26 | 1.53 (0.98-2.26) | 1.74 (1.00-2.97) | 11 | 0.59 (0.28-1.08) | 1.41 (0.58-3.20) | 9 | 0.60 (0.27-1.13) | 2.90 (0.99-8.27) | |
| High | More ethnic | 120 | 0.86 (0.70-1.03) | 1.00 (reference) | 87 | 0.59 (0.47-0.74) | 1.00 (reference) | 15 | 0.14 (0.07-0.24) | 1.00 (reference) |
| Intermediate | 62 | 1.19 (0.89-1.56) | 1.39 (0.98-1.95) | 41 | 0.75 (0.52-1.06) | 1.27 (0.82-1.91) | 11 | 0.24 (0.12-0.44) | 1.74 (0.70-4.30) | |
| Less ethnic | 87 | 1.72 (1.36-2.16) | 2.02 (1.48-2.73) | 49 | 0.90 (0.65-1.21) | 1.51 (1.02-2.20) | 21 | 0.46 (0.27-0.72) | 3.29 (1.54-7.34) | |
| ENCLAVE*SES‡ | ||||||||||
| More Ethnic/Low SES | 38 | 0.88 (0.62-1.21) | 1.00 (reference) | 19 | 0.42 (0.25-0.66) | 1.00 (reference) | 9 | 0.21 (0.09-0.39) | 1.00 (reference) | |
| More Ethnic/High SES | 120 | 0.86 (0.70-1.03) | 0.97 (0.67-1.46) | 87 | 0.59 (0.47-0.74) | 1.42 (0.85-2.51) | 15 | 0.14 (0.07-0.24) | 0.68 (0.26-1.79) | |
| Intermediate/Low SES | 15 | 0.99 (0.55-1.66) | 1.13 (0.57-2.14) | 11 | 0.66 (0.33-1.21) | 1.58 (0.67-3.59) | -- | -- | -- | |
| Intermediate/High SES | 62 | 1.19 (0.89-1.56) | 1.36 (0.87-2.13) | 41 | 0.75 (0.52-1.06) | 1.80 (0.99-3.37) | 11 | 0.24 (0.12-0.44) | 1.17 (0.43-3.27) | |
| Less Ethnic/Low SES | 26 | 1.53 (0.98-2.26) | 1.74 (1.00-2.97) | 11 | 0.59 (0.28-1.08) | 1.41 (0.58-3.20) | 9 | 0.60 (0.27-1.13) | 2.90 (0.99-8.27) | |
| Less Ethnic/High SES | 87 | 1.72 (1.36-2.16) | 1.96 (1.31-3.00) | 49 | 0.90 (0.65-1.21) | 2.14 (1.22-3.93) | 21 | 0.46 (0.27-0.72) | 2.22 (0.94-5.64) | |
*
Per 100,000 person-years and standardized to the 2000 U.S. standard population
§
More ethnic (Enclave Quintile 5); Intermediate (Enclave Quintile 4); Less ethnic (Enclave Quintile 1-3)
--Per confidentiality regulations of the California Cancer Registry, case counts and rates based on fewer than 5 cases are suppressed, and statistics are not computed.
‡
Low SES comprises the lowest SES tertile; high SES comprises the middle and highest SES tertiles.
Bolding denotes statistical significance.