Table S1.

Risk of bias and quality assessment of the included studies

Author	Random sequence generation	Allocation concealment	Blinding of participants and personnel	Blinding of outcome assessment	Incomplete outcome data	Selective reporting	Other bias
Mima et al26	Low bias	Uncertain	High bias	Low bias	Low bias	High bias	Low bias
Johnson et al27	Uncertain	Uncertain	Low bias	Low bias	High bias	Low bias	Low bias
Nairn28	Uncertain	Uncertain	Low bias	Low bias	Low bias	Low bias	Uncertain
Goins et al29	Low bias	Uncertain	High bias	High bias	High bias	Uncertain	Uncertain
Hoppe20	Low bias	Uncertain	High bias	Uncertain	High bias	Low bias	High bias
Flynn et al30	Low bias	Low bias	High bias	Low bias	Low bias	Low bias	High bias
Moshi et al31	Low bias	Uncertain	Uncertain	Low bias	High bias	Uncertain	Uncertain
Pons et al32	Uncertain	Uncertain	High bias	Low bias	High bias	Uncertain	Uncertain
Nyst et al33	Low bias	Low bias	Uncertain	Uncertain	High bias	Uncertain	High bias
Meunier et al34	Low bias	Low bias	High bias	Uncertain	Uncertain	Low bias	Uncertain
Blomgren et al35	High bias	Uncertain	High bias	Low bias	High bias	Uncertain	High bias