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RNase mass mapping using 80 Å pore size superficially porous particles. (A) IP RP HPLC analysis of 7–10 mer oligonucleotides on superficially porous particles, 80 Å pore size using gradient 3. (B) LS ESI MS analysis of RNase a mass mapping of 500 nt ssRNA in vitro transcript. 500 ng of ssRNA was analysed using gradient 4. The identified oligoribonucleotides are highlighted.
