Table 1.
Changes in study outcomes from baseline (the end of the 1-month insulin-adjustment phase of each arm) to week 12, adjusted for the baseline value of the outcome (presented in parentheses). Values are mean ± SEM, with negative changes indicating a decrease and positive changes an increase.
| Glargine | NPH | P | |
|---|---|---|---|
| Hemoglobin A1c, % | −0.2±0.1 (6.4±0.2) |
−0.2±0.1 (6.6±0.2) |
.96 |
| Fasting plasma glucose, mg/dl | −8±2 (123±4) |
−0±2 (125±5) |
.03 |
| 2h postprandial glucose, mg/dl | −6±5 (150 ± 6) |
−8±5 (155±9) |
.85 |
| Weight, kg | +1.2±0.5 (64.3±2.4) |
+0.2±0.5 (65.7±2.5) |
.07 |
| Fat mass by DEXA, kg | +0.7±0.4 (16.1±1.4) |
+0.4±0.4 (16.7±1.5) |
.09 |
| Lean mass by DEXA, kg | +0.3±0.2 (45.7±1.9) |
+0.1±0.2 (45.7±2.0) |
.50 |