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Conservation of the proviral CTCF-BS among various HTLV-1 strains (A) and in HTLV-1–infected cells [PBMCs of patients with ATL or asymptomatic carriers (AC) or ATL-derived cell lines] (B). A hyphen (-) denotes the same sequence as the consensus nucleotide. This vCTCF sequence has strong similarity to the human genome CTCF core motif consensus (Fig. S4; similarity score of 88%).
