Table S2.
Histone deacetylase inhibitors included in the compound library
| HDAC inhibitor | Hit? | HDAC target |
| Panobinostat (LBH-589) | Yes | HDAC1, HDAC2, HDAC3, HDAC6 |
| AR-42 (HDAC-42) | Yes | Pan inhibitor |
| Trichostatin A (TSA) | Yes | Pan inhibitor |
| Vorinostat (SAHA) | Yes | HDAC1, HDAC2, HDAC3, HDAC6 |
| Entinostat (MS-275) | Yes | HDAC1, HDAC2, HDAC3, HDAC9 |
| Abexinostat (PCI-24781) | Yes | HDAC1, HDAC2, HDAC3, HDAC6, HDAC10 |
| Dacinostat (NVP-LAQ824) | Yes | HDAC1, HDAC3, HDAC4, HDAC6 |
| Quisinostat (JNJ-26481585) | Yes | Pan inhibitor |
| CUDC-101 | Yes | Pan-HDAC, EGFR, HER2 |
| Pracinostat (SB939) | Yes | Pan inhibitor |
| Givinostat (ITF2357) | Yes | HDAC1, HDAC2, HDAC3, HDAC4, HDAC6, HDAC7 |
| CUDC-907 | Yes | Pan-HDAC and PI3K |
| M344 | Yes | Pan inhibitor |
| Romidepsin (FK228) | Yes | HDAC1, HDAC2, HDAC3, HDAC8 |
| Tubastatin HCl | No (negative control) | HDAC6 |
| Belinostat (PXD101) | No | HDAC1, HDAC2, HDAC3, HDAC6 |
| Mocetinostat (MGCD0103) | No | HDAC1, HDAC2 |
| Droxinostat | No | HDAC3, HDAC6, HDAC8 |
| MC1568 | No | HDAC4, HDAC5, HDAC7, HDAC9 |
| PCI-34051 | No | HDAC8 |
| Tacedinaline (CI-994) | No | HDAC1, HDAC2, HDAC3 |
Histone deacetylase inhibitors, specification of screening status, and recognized HDAC target specificity are shown.