Table S1.
hPER3-P415A/H417R flies exhibit earlier activity offset time vs. hPER3-WT flies
| UAS transgene | GAL4 driver | Time of activity onset (ZT) | Time of activity offset (ZT) | n |
| UASPER3-WT/+ (2) | WT | 22.6 ± 0.2 | 13.9 ± 0.0 | 30 |
| UASPER3-WT (2) | timGAL4 | 23.2 ± 0.2 | 14.0 ± 0.1 | 39 |
| UASPER3-WT (2) | cryGAL4-16 | 23.2 ± 0.2 | 15.2 ± 0.2 | 40 |
| UASPER3-WT/+ (3) | WT | 22.6 ± 0.2 | 13.9 ± 0.1 | 30 |
| UASPER3-WT/+ (3) | timGAL4 | 23.3 ± 0.1 | 14.2 ± 0.1 | 39 |
| UASPER3-WT/+ (3) | cryGAL4-16 | 23.1 ± 0.2 | 14.7 ± 0.2 | 40 |
| UASPER3-P415A/H417R/+ (1) | WT | 22.7 ± 0.2 | 13.7 ± 0.0 | 30 |
| UASPER3-P415A/H417R/+ (1) | timGAL4 | 22.7 ± 0.2*,† | 13.6 ± 0.0*,† | 40 |
| UASPER3-P415A/H417R/+ (1) | cryGAL4-16 | 23.0 ± 0.2 | 14.0 ± 0.0*,† | 40 |
| UASPER3-P415A/H417R (7) | WT | 23.3 ± 0.1 | 13.8 ± 0.0 | 32 |
| UASPER3-P415A/H417R (7) | timGAL4 | 23.1 ± 0.1 | 13.7 ± 0.0*,† | 40 |
| UASPER3-P415A/H417R (7) | cryGAL4-16 | 22.9 ± 0.2 | 13.9 ± 0.1*,† | 37 |
| WT | timGAL4/+ | 23.3 ± 0.2 | 14.3 ± 0.2 | 24 |
| WT | cryGAL4-16 | 23.2 ± 0.1 | 14.5 ± 0.2 | 23 |
See also Fig. S1. The numbers in parentheses indicate the line number for different UASPER3 transgenic lines.
*
Student’s t test compared with PER3-WT (2)-expressing lines; P < 0.05.
†
Student’s t test compared with PER3-WT (3)-expressing lines; P < 0.05.