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. 2016 Feb 29;113(11):2819–2826. doi: 10.1073/pnas.1521570113

Fig. 1.

Fig. 1.

LMF theory-based thermodynamic cycle for solvation. The bottom leg of the cycle corresponds to inserting a solute (S) into a mobile solvent (M), both of which have short- and long-ranged interactions. This solvation process results in a free energy change Ω˘. The top leg of the cycle depicts the insertion of a renormalized solute (SR) into a short-ranged mobile solvent (M0), and the solvation free energy in this mimic system is Ω˘. The sum of the free energies of the paths depicted by green arrows is ΔΩLMF=Ω˘Ω˘R, as described in the text.