Figure 3.

CART analysis of relationship between multiple immunological markers and OS of MM patients from NIBIT-M1 study CART analysis, a recursive partitioning non parametric method was applied to assess any association among OS of MM patients and multiple immunological parameters, such as the presence at baseline of sNKG2DLs and the frequency of circulating T cell subsets (CD3⁺CD4⁺CD45RO⁺BTLA⁺, CD3⁺CD4⁺4–1BB, and Th17). The values of the 75th percentile of % of positive T cells were used to discriminate patients' groups. Patients were also divided in two groups based on the presence or the absence of sULBP-1 and sULBP-2 in the serum at baseline.