. 2015 Aug 12;5(2):e1071007. doi: 10.1080/2162402X.2015.1071007

Table 2.

Relationship between the frequency at W12 versus baseline of circulating T cell subsets and clinical responses of MM patients.

T cell subset	DC	Mean^a	Standard Error	P
CD3⁺CD45RO⁺BTLA⁺	Yes	258.54	20.97	0.03
	No	−24.54	115.63
CD3⁺CD4⁺CD45RO⁺BTLA⁺	Yes	75.08	23.14	0.05
	No	−21.50	26.96
CD3⁺CD4⁺CXCR3⁺CCR5⁺ CCR6⁺IL-23R⁺	Yes	95.06	56.69	0.05
	No	−25.76	17.49
CD3⁺BTLA⁺CTLA-4⁺	Yes	20.70	81.77	0.03
	No	−27.44	35.13
T cell subset	OR	Mean^a	Standard Error	P
CD3⁺ CD4⁺CD45RO⁺ICOS⁺	Yes	319.91	101.46	0.05
	No	96.05	51.78
CD3⁺CD4⁺CD45RO⁺BTLA⁺	Yes	81.49	31.51	0.05
	No	1.62	24.11
CD3⁺CD8⁺CD45RO⁺BTLA⁺	Yes	67.90	25.59	0.05
	No	−4.92	22.79
CD3⁺CD45RO⁺PD-1⁺	Yes	256.87	101.18	0.05
	No	38.96	36.48
CD3⁺CD8⁺CD45RO⁺PD-1⁺	Yes	170.57	72.80	0.05
	No	21.14	30.78

DC: disease control; OR: objective response; ^a relative difference of the mean of the % of positive cells between baseline and W12 in PBMCs from melanoma patients; number of patients with DC = 19; number of patients without DC = 12; number of patients with = OR = 14; number of patients without OR = 17.