Figure 3.

The density of NK cells and COX-2 expression are negatively associated in GC patient samples. (A) Serial sections of paraffin-embedded GC samples stained with anti-CD57 or anti-COX-2 Ab. Different levels of COX-2 expression can be observed in the intratumoral regions: a, strong or positive; c, none, slight or negative. Serial sections stained with anti-CD57 Ab: b, low density; d, high density. (B) Statistical analysis of the number of NK cells infiltrated into the intratumoral region with different levels of COX-2 expression. (C, D) Cumulative OS and DFS curves of the patients positive or negative for COX-2 expression.