Skip to main content
. Author manuscript; available in PMC: 2016 Mar 21.
Published in final edited form as: Biochemistry. 2015 Sep 11;54(38):5815–5827. doi: 10.1021/acs.biochem.5b00746

Figure 1.

Figure 1

Functional characterization of cyclophilins. (a) Titrations o the peptide substrate into 15N-labeled cyclophilins. 15N HSQC spectra were collected on 0.5 mM cyclophilin with 0 mM (red), 0.1 mM (orange), 0.2 mM (green), 0.5 mM (cyan), 1 mM (blue), and 2 mM (violet) unlabeled peptide substrate. (b) ZZ-exchange spectra for residue Leu 7, collected with mixing times of 0 ms (black) and 144 ms (red) on 1 mM 15N-labeled peptide with the addition of 20 µM cyclophilin