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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: J Med Primatol. 2016 Feb 22;45(2):85–91. doi: 10.1111/jmp.12210
Case # Tumor # Signalment Gross
appearance
Amyloid
in tumor
Islet
amyloidosis
Insulin Gastrin Glucagon Somatostatin VIP Synaptophysin Chromogranin Pancreatic
polypeptide
Solid Capsule Packeting Very
vascular
Mitotic
rate
Acinar
pattern
Thick
stroma
Focal (F)
or
Diffuse
(D)
Granularity Size on
slide
1 1 23 yr F 3 cm
diameter
no no mild
multifocal
negative mild
multifocal
positive negative positive positive negative ++ + 1 per 10
fields
+ F 1.5 × 1cm
2 NS no no mild
multifocal
negative negative mild
multifocal
negative positive positive mild
multifocal
+ + ++ 0 per 10
fields
D 5mm
2 3 28 yr F NS no no mild
multifocal
negative negative negative negative positive positive negative + + + 1 per 10
fields
F 5mm
4 NS no no mild
multifocal
negative mild
multifocal
mild
multifocal
negative positive positive negative + ++ 0 + 2mm
5 NS no no mild
multifocal
negative mild
multifocal
mild
multifocal
negative positive positive negative + + ++ 0 1mm
6 NS no no mild
multifocal
negative mild
multifocal
mild
multifocal
negative positive positive negative + ++ 0 1 ×
0.5mm
3 7 23 yr F NS no no mild
multifocal
negative negative mild
multifocal
negative positive positive mild
multifocal
+ + + 1 per 10
fields
F 7 × 5mm
4 8 26 yr F NS no yes mild
multifocal
negative mild
multifocal
mild
multifocal
negative positive positive negative + + 0 + 2 × 1mm
9 NS no yes mild
multifocal
negative negative negative negative positive positive negative + + ++ 0 1.5 ×
1mm
5 10 24 yr F NS no no negative negative negative negative negative positive positive negative + + ++ 0 2 × 1mm
6 11 17 yr F NS no no positive negative ND ND ND ND ND ND + ++ 0 0.5mm
7 12 26 yr F NS yes yes mild
multifocal
negative negative negative negative positive positive negative + ++ 1 per 10
fields
+ 2mm
8 13 20 yr F NS no no mild
multifocal
negative negative negative negative positive positive negative + + 0 1mm
9 14 12 yr F NS no yes negative negative negative negative negative positive positive negative + + ++ 0 + 1 ×
0.5mm
10 15 19 yr F NS no yes negative negative negative negative negative positive positive negative + + 0 1 ×
0.5mm
11 16 24 yr F NS no yes positive negative negative negative negative positive positive negative + + 0 0.75mm
12 17 26 yr F NS yes yes negative negative negative negative negative positive ND negative + ++ 0 1mm
18 NS no yes positive negative negative negative ND ND ND ND + + 0 + 0.5mm
19 NS yes yes positive negative mild
multifocal
mild
multifocal
negative ND ND ND + + 0 + 1 ×
0.5mm
20 NS no yes mild
multifocal
negative negative mild
multifocal
negative positive ND negative + ++ 1 1mm
21 NS no yes negative negative negative negative negative ND ND ND + + 0 1 ×
0.5mm
NS = Not
seen
ND = Not
done
ND = Not
done
ND = Not
done
ND = Not
done
ND = Not
done
ND = Not
done