Table 4. Multivariate Analyses.
Time-varying course of ADHD and DBD predicting time to recovery and recurrence in mania and depression respectively (restricted to a maximum of 5 episodes).
Mania (Maximum 5 Episodes) |
Depression (Maximum 5 Episodes) |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Event n | HR | p | 95% CI | Event n | HR | p | 95% CI | |||
|
|
|||||||||
ADHD PSR | ||||||||||
Recovery | 275 | 0.58 | 0.0233 | 0.36 - | 0.93 | 510 | 0.76 | 0.20 | 0.50 - | 1.15 |
Recurrence | 249 | 1.94 | 0.0360 | 1.03 - | 3.62 | 527 | 1.55 | 0.0067 | 1.12 - | 2.10 |
|
|
|||||||||
DBD PSR | ||||||||||
Recovery | 275 | 0.46 | 0.06 | 0.21 - | 1.02 | 510 | 0.82 | 0.42 | 0.50 - | 1.34 |
Recurrence | 249 | 2.14 | 0.0324 | 1.06 - | 4.33 | 527 | 1.56 | 0.0204 | 1.07 - | 2.25 |
|
|
|||||||||
ADHD × DBD | ||||||||||
Recovery | 275 | 1.36 | 0.0350 | 1.03 - | 1.78 | 510 | 1.05 | 0.59 | 0.88 - | 1.25 |
Recurrence | 249 | 0.80 | 0.10 | 0.62 - | 1.04 | 527 | 0.86 | 0.0414 | 0.75 - | 0.99 |
|
|
Notes:
The above analyses included covariates: BP age of onset, living with biological parents, race, SES, BPNOS status at intake, family history of mania, and duration of illness.
ADHD = Attention Deficit Hyperactivity Disorder, DBD = Disruptive Behavior Disorders (ODD and CD).