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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Kidney Int. 2016 Jan 6;89(4):949–955. doi: 10.1016/j.kint.2015.11.015

FIGURE 3. TRPP2D511V is degraded in lysosomes.

FIGURE 3

a) Western blot analysis shows that TRPP2D511V is more abundant in cells treated with 200 µM chloroquine (CQ) compared with control cells. b) MG-132 (210 µM) does not affect TRPP2D511V protein levels. c) Group data from a and b show that chloroquine significantly increases abundance of TRPP2D511V (mean=1,461%; n=4; p=0.003), whereas MG132 shows no effect (mean=108%; n=4).