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HCA inhibits bronchial epithelial stretch-induced injury. Hypercapnic acidosis decreased 24-h stretch-induced interleukin-8 secretion (a, b), preserved membrane integrity as assessed by epithelial LDH leakage (c, d), and maintained cell viability (e, f) in human bronchial epithelial cells and BEAS-2B cells, respectively. Note: *P < 0.05 versus normocapnia for each condition
