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HCA attenuates alveolar epithelial injury following 24 and 120 h of cyclic mechanical stretch. HCA decreased stretch-induced activation of NF-κB (a), attenuated IL-8 secretion (b), reduced epithelial LDH leakage (c), and maintained cell viability (d) following 24 and 120 h of cyclic mechanical stretch in A549 alveolar epithelial cells. Note: *P < 0.05 versus normocapnia for each condition. Abbreviations: Sham unstretched cells
