Table 2. Sample description.
| Characteristic | Discovery sample (N=85) | Blood replication sample (N=45) | Cross-validation sample (N=255) |
|---|---|---|---|
| Sex (% of female) | 50.5 | 80 | 45 |
| Age (mean in years, range) | 33 (18 to 69) | 28 (19 to 45) | 17 (15 to 18) |
| Caucasian ethnicity (%) | 100 | 38 | 100 |
| Current MDD (%) | 0 | 24 | NA |
| Childhood trauma (mean total score, range) | 31.9 (24 to 63) | 56.8 (25 to 110) | NA |
| Cortisol stress reactivity (mean AUCi, range) | 242.3 (−1,030 to 1,876) | 1,185 (378 to 2,045) | −37 (−426 to 313) |
AUCi, area under the curve (AUC) with respect to the increase; MDD, major depressive disorder; NA, not applicable.