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. 2016 Mar 22;6:23344. doi: 10.1038/srep23344

Figure 2. Protons alter GluN1/GluN3A desensitisation kinetics.

Figure 2

(a) Glycine-elicited currents recorded at pH 7.4 (black) and pH 6.8 (red) superimposed and normalized to peak; bar graph summarizes changes in the weighted desensitisation time course (τD). (b) Glycine double-pulse current traces elicited at pH 7.4 and pH 6.8; Δt was 3 s with 2 s increments for pH 7.4, and 3 s with 1 s increments for pH 6.8; curves represent exponential fits to average Ipk values. (c) Summary data for time constant of recovery from desensitisation (τrec) (left) and time-dependence of peak current (Ipk) recovery from desensitisation (right). Values are means ± SEM, sample size is in bars; *P < 0.05.