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. 2015 Nov 10;5:1–15. doi: 10.1016/j.bbacli.2015.11.001

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© 2015 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 1 — Loci of amplified oncogenes and metabolic/growth factor genes. The chromosomal loci (red rectangles) of twenty oncogenes amplified at least 3.00-fold and metabolic/growth factor (MTB/GF) genes are shown. The copy number (CN) amplification of oncogenes in each glioblastoma (GB) are depicted with small solid black rectangles (1.00 times normal per rectangle) and open arrows (10.00 times normal per arrow) as indicated in comparison to normal brain DNA. The highest CN gains occurred for EGFR. The superscript (†) indicates the MTB/GF genes with expression data but no CN data.