Table 3.

Discrimination and Reclassification of Coronary, Aortic, and Valvular Calcification for Major CHD Events

Major CHD Model: NRI Using Risk Categories of <0.025, 0.025 to <0.05, 0.05 to <0.10, ≥0.10	C‐Statistic	NRI (95% CI)	Proportion Events/Nonevents Classified Correctly
RF only	0.78	—	—
RF+log CAC	0.82	0.32 (0.11–0.53)	0.33/−0.02
RF+CAC cat	0.83	0.22 (0.01–0.42)	0.24/−0.02
RF+log AAC	0.79	0.12 (0.01–0.24)	0.14/−0.02
RF+log TAC	0.80	0.11 (−0.03 to 0.24)	0.11/−0.002
RF+log MVC	0.79	0.11 (−0.04 to 0.26)	0.11/−0.003
RF+log AVC	0.79	−0.03 (−0.19 to 0.11)	−0.03/0.0003

AAC indicates abdominal aorta calcification; AVC, aortic valve calcification; CAC, coronary artery calcification; cat, categorical; CHD, coronary heart disease; MVC, mitral valve calcification; NRI, net reclassification index; RF, adjusted for Framingham risk factors; TAC, thoracic aorta calcification.