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. 2016 Feb 8;5(2):e002858. doi: 10.1161/JAHA.115.002858

Table 2.

Cross‐Sectional Correlates of GGT

Pearson Correlation r (95% CI)a Percentage Difference (95% CI) in GGT Levels Per 1 SD Higher or Compared With Reference Category of Correlateb
Loge GGT, U/L
Questionnaire/prevalent conditions
Age at survey, y −0.03 (−0.08 to 0.02) −2% (−5 to 1)
Alcohol consumption, g/week 0.27 (0.23–0.31)*** 19% (15–22)***
History of diabetes
No Ref
Yes 47% (28–69)***
Smoking status
Other Ref
Current 11% (4–18)**
Left ventricular hypertrophy
No Ref
Yes −4% (−28 to 28)
History of hypertension
No Ref
Yes 27% (20–36)***
History of CHD
No Ref
Yes 17% (9–25)***
Use of antihypertensives
No Ref
Yes 24% (15–34)***
Medication for dyslipidemia
No Ref
Yes 25% (−14 to 81)
Physical measurements
BMI, kg/m2 0.34 (0.30–0.38)*** 24% (21–27)***
SBP, mm Hg 0.21 (0.17–0.26)*** 14% (11–18)***
DBP, mm Hg
Resting heart rate, bpm 0.14 (0.10–0.19)*** 9% (6–13)***
Lipid markers
Total cholesterol, mmol/L 0.10 (0.05–0.14)*** 6% (3–9)***
HDL‐C, mmol/L −0.04 (−0.09 to 0.01) −2% (−5 to 0)
Loge triglycerides, mmol/L 0.26 (0.21–0.30)*** 18% (14–21)***
Metabolic and inflammatory markers
Fasting plasma glucose, mmol/L 0.21 (0.16–0.25)*** 14% (11–17)***
Serum creatinine, μmol/L 0.00 (−0.04 to 0.05) 0% (−3 to 3)
Loge CRP, mg/L 0.27 (0.22–0.31)*** 18% (15–21)***

BMI indicates body mass index; CHD, coronary heart disease; CRP, C‐reactive protein; DBP, diastolic blood pressure; HDL‐C, high‐density lipoprotein cholesterol; GGT, γ‐glutamyltransferase; Ref, reference.

Asterisks indicate the level of statistical significance: **P<0.01; ***P<0.001.

a

Pearson correlation coefficients between loge GGT and the row variables.

b

Percentage change in GGT levels per 1‐SD increase in the row variable (or for categorical variables, the percentage difference in mean GGT levels for the category vs the reference) adjusted for age.