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. 2016 Feb 8;5(2):e002796. doi: 10.1161/JAHA.115.002796

Figure 6.

Figure 6

Allogeneic CDCs prevent hypertrophy, decrease infarct size, and salvage myocardium, as assessed by postmortem histology. Representative short‐axis heart slices of a placebo‐ and a CDC‐treated pig after incubation with TTC. Viable myocardium stains brick red, whereas scarred myocardium appears white (A). Comparison of scar transmurality (B), myocardial salvage index (C), scar mass (D), and percent IS/AAR (E) at 2 months in placebo and CDC groups. Comparison of remote area (as percent of LV) at 2 months in placebo and CDC groups (F). Cardiomyocyte cross‐sectional area in the remote zone (G and H). AAR indicates area at risk; AU, astronimcal unit; CDCs, cardiosphere‐derived cells; IS, infarct size; LV, left ventricle; TTC, 2,3,5‐triphenyl tetrazolium chloride. Values are means±SEM. *P<0.05 and **P<0.01 between 2 groups. Scale bar in (A) is 1 cm.