Table 4.
Genotypes and Alleles Frequency Distribution for rs584981, rs641836, and rs11237379 NDUFC2 Polymorphisms in Early‐Onset Ischemic Stroke Patients and in Controls
| SNP | Controls (n=1165) n (%) | Stroke Patients (n=484) n (%) | P Value |
|---|---|---|---|
| rs584981 | |||
| TT | 696 (59.7) | 294 (60.7) | 0.846a |
| TC | 414 (35.5) | 170 (35.1) | 0.705b |
| CC | 55 (4.7) | 20 (4.1) | 0.601c |
| C frequency | 0.225 | 0.217 | |
| H‐W | 0.450 | 0.594 | |
| rs641836 | |||
| GG | 799 (68.6) | 309 (63.8) | 0.167a |
| GA | 321 (27.6) | 155 (32.0) | 0.062b |
| AA | 45 (3.9) | 20 (4.1) | 0.798c |
| A frequency | 0.176 | 0.201 | |
| H‐W | 2.752 | 0.010 | |
| rs11237379 | |||
| CC | 251 (21.5) | 94 (19.4) | 0.058a |
| CT | 590 (50.6) | 227 (46.9) | 0.334b |
| TT | 324 (27.8) | 163 (33.7) | 0.017c |
| C frequency | 0.469 | 0.429 | |
| H‐W | 0.332 | 0.874 | |
H‐W indicates Hardy‐Weinberg; SNP, single‐nucleotide polymorphism.
a
According to the additive model.
b
According to the dominant model.
c
According to the recessive model.