Table 6.
Changes in BMI, Weight, and VAT and SAT Measurements From Baseline Prolactin
| Outcomea | Modelb | Women | P Value | Men | P Value | Overall | P Value |
|---|---|---|---|---|---|---|---|
| BMI change, kg/m2 | Model 1 | −0.2 (−0.5 to 0.1) | 0.20 | −0.2 (−0.5 to 0.2) | 0.34 | −0.2 (−0.4 to 0.0) | 0.10 |
| Model 2 | −0.2 (−0.5 to 0.1) | 0.17 | −0.1 (−0.4 to 0.2) | 0.60 | −0.2 (−0.4 to 0.0) | 0.12 | |
| Weight change, kg | Model 1 | −0.4 (−1.1 to 0.3) | 0.27 | −0.4 (−1.4 to 0.6) | 0.41 | −0.4 (−1.0 to 0.2) | 0.18 |
| Model 2 | −0.5 (−1.2 to 0.3) | 0.22 | −0.2 (−1.2 to 0.8) | 0.70 | −0.4 (−0.9 to 0.2) | 0.21 | |
| VAT volume change, cm3 | Model 1 | −23.5 (−77.9 to 30.9) | 0.40 | −4.6 (−125.4 to 116.1) | 0.94 | −14.1 (−73.5 to −45.3) | 0.64 |
| Model 2 | −27.5 (−82.6 to 27.5) | 0.33 | 7.8 (−114.4 to 130.1) | 0.90 | −15.2 (−75.5 to 45.0) | 0.62 | |
| Model 3 | −27.0 (−81.9 to 27.9) | 0.34 | 9.1 (−112.0 to 130.1) | 0.88 | −15.2 (−75.3 to 45) | 0.62 | |
| SAT volume change, cm3 | Model 1 | −41.1 (−133.8 to 51.5) | 0.38 | −57.9 (−158.0 to 42.2) | 0.26 | −47.8 (−112.5 to 16.9) | 0.15 |
| Model 2 | −50.8 (−143.8 to 42.2) | 0.29 | −36.2 (−137.0 to 64.5) | 0.48 | −42.2 (−107.5 to 23.0) | 0.21 | |
| Model 3 | −49.8 (−143.0 to 43.3) | 0.30 | −36.4 (−137.2 to 64.5) | 0.48 | −42.2 (−107.5 to 23.1) | 0.21 | |
| VAT attenuation change, HU | Model 1 | 0.19 (−0.34 to 0.72) | 0.48 | 0.57 (−0.17 to 1.30) | 0.13 | 0.34 (−0.08 to 0.76) | 0.12 |
| Model 2 | 0.17 (−0.36 to 0.70) | 0.53 | 0.45 (−0.30 to 1.19) | 0.24 | 0.27 (−0.16 to 0.70) | 0.21 | |
| Model 3 | 0.19 (−0.32 to 0.70) | 0.46 | 0.38 (−0.34 to 1.11) | 0.30 | 0.26 (−0.15 to 0.67) | 0.21 | |
| SAT attenuation change, HU | Model 1 | 0.01 (−0.35 to 0.37) | 0.94 | −0.03 (−0.52 to 0.46) | 0.90 | −0.01 (−0.30 to 0.27) | 0.94 |
| Model 2 | 0.01 (−0.36 to 0.37) | 0.97 | −0.18 (−0.67 to 0.32) | 0.49 | −0.06 (−0.35 to 0.22) | 0.66 | |
| Model 3 | 0.00 (−0.36 to 0.37) | 0.98 | −0.18 (−0.67 to 0.32) | 0.49 | −0.07 (−0.35 to 0.22) | 0.65 |
All sex‐interaction P>0.54. BMI indicates body mass index; HU, Hounsfield units; SAT, subcutaneous adipose tissue; VAT, visceral adipose tissue.
a
Estimates given change in dependent variable associated with each additional 5‐mg/dL increment in prolactin.
b
Model 1 included age, sex, baseline value of the variable. Model 2 included model 1 plus smoking status and in women, menopausal status. Model 3 included model 2 plus BMI.