Table 1.
Patient Demographics
| All Subjects (n=31) |
Placebo (n=12) |
Active (n=14) |
|||
|---|---|---|---|---|---|
| Baseline | Baseline | Post | Baseline | Post | |
| Age (yrs) | 59±2 | 56±2 | - | 59±3 | - |
| Gender (% male) | 26 (84) | 9 (82) | - | 12 (86) | - |
| BMI (kg/m2) | 28±1 | 28±2 | 29±2 | 30±1 | 30±1 |
| Percent Fat (%) | 31±1 | 32±2 | 32±3 | 32±2 | 31±1 |
| Heart Rate (bpm) | 70±2 | 68±2 | 72±3 | 71±3 | 71±3 |
| Systolic BP (mmHg) | 114±3 | 114±5 | 115±5 | 114±5 | 110±4 |
| Diastolic BP (mmHg) | 67±2 | 69±3 | 69±3 | 68±3 | 66±2 |
| Etiology (#(%)) | |||||
| Ischemic cardiomyopathy | 16 (52) | 4 (33) | - | 8 (57) | - |
| Dilated cardiomyopathy | 12 (39) | 6 (50) | - | 5 (36) | - |
| Other | 3 (10) | 2 (17) | - | 1 (7) | - |
| Medication (#(%)) | |||||
| Beta Blocker | 28 (90) | 11 (92) | - | 12 (86) | - |
| ACE inhibitors/ARB | 26 84) | 11 (92) | - | 10 (71) | - |
| Spironolactone | 6 (19) | 1 (8) | - | 4 (29) | - |
| Digoxin | 16 (52) | 6 (50) | - | 7 (50) | - |
| Diuretics | 21 (68) | 11 (92) | - | 6 (43) | - |
| Aspirin | 21 (68) | 6 (50) | - | 11 (79) | - |
| Statins | 19 (61) | 7 (58) | - | 8 (57) | - |
| Insulin | 5 (16) | 3 (25) | - | 2 (14) | - |
| Coumadin | 9 (29) | 3 (25) | - | 4 (29) | - |
Post represents 3 months following the intervention. Values expressed at Mean ± SEM