Table 4.

Echocardiographic Parameters

	All subjects (n=31)	Placebo (n=12)		Active (n=14)
	Baseline	Baseline	Post	Baseline	Post
LV end-diastolic diameter (mm)	66 ± 2	67 ± 3	66 ± 3	65 ± 3	63 ± 3
Left ventricular ejection fraction (%)	28 ± 1	30 ± 2	37 ± 3	26 ± 2	34 ± 3
Left ventricular dP/dt	680 ± 16	708 ± 25	779 ± 27	665 ± 24	733 ± 31
Mitral valve deceleration time (ms)	212 ± 9	192 ± 16	225 ± 12	218 ± 13	224 ± 9
Pre-A/E	1.3 ± 0.1	1.3 ± 0.2	1.3 ± 0.1	1.2 ± 0.1	1.1 ± 0.1
Left ventricular E/E’	15 ± 1	15 ± 1	13 ± 1	15± 1	14 ± 1
Right ventricular E/E’	10.3 ± 0.5	9.5± 0.9	9.7 ± 1.1	11.0 ± 0.6	9.3 ± 0.6

Post represents 3 months following the intervention. Values expressed at Mean ± SEM