Table I.
Reference | Sex | No. of patients | Age | Clinical context | Therapeutic regimen | Therapy received for acne fulminans |
---|---|---|---|---|---|---|
Genetic Disorders | ||||||
Hartmann and Burg, 19891 | M | 1 | 19 | Klinefelter syndrome | Testosteron enantat 500 mg every 2 wk over 18 mo | Isotretinoin therapy over 16 weeks |
Wollina et al, 20054 | M | 1 | 12 | Marfan syndrome | Testosterone 50 mg every 2 wk for 6 mo | Clindamycin 300 mg, prednisolone 1 mg/kg, and isotretinoin 0.5 mg/kg. Prednisolone switched for dapsone 100 mg/d (disagreement of patient's mother to continue steroid treatment) |
Current case | M | 2 | 18 | Kallmann syndrome | Testosterone 250 mg once a mo over 10 mo | Systemic corticosteroid 0.5 mg/kg/d, isotretinoin 0.06 mg/kg/d |
Tall Stature Treatment | ||||||
Traupe et al, 19882 | M | 3 | 13-16 | Excessively tall stature | High doses of testosterone | Oral isotretinoin and topical steroid (2 cases) Systemic corticosteroid (1 case) |
Weimann and Bohles, 19993 | M | 1 | 13 | Hereditary tall stature treated with high dose of testosterone | Testosterone 250 mg once a wk over 6 mo | Isotretinoin therapy (0.3 mg/kg/d), methylprednisolone and cefaclor |