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. 2014 Oct 18;1(1):27–29. doi: 10.1016/j.jdcr.2014.10.005

Table I.

Demographic and clinical data of patients with testosterone-induced acne fulminans

Reference Sex No. of patients Age Clinical context Therapeutic regimen Therapy received for acne fulminans
Genetic Disorders
 Hartmann and Burg, 19891 M 1 19 Klinefelter syndrome Testosteron enantat 500 mg every 2 wk over 18 mo Isotretinoin therapy over 16 weeks
 Wollina et al, 20054 M 1 12 Marfan syndrome Testosterone 50 mg every 2 wk for 6 mo Clindamycin 300 mg, prednisolone 1 mg/kg, and isotretinoin 0.5 mg/kg.
Prednisolone switched for dapsone 100 mg/d (disagreement of patient's mother to continue steroid treatment)
 Current case M 2 18 Kallmann syndrome Testosterone 250 mg once a mo over 10 mo Systemic corticosteroid 0.5 mg/kg/d, isotretinoin 0.06 mg/kg/d
Tall Stature Treatment
 Traupe et al, 19882 M 3 13-16 Excessively tall stature High doses of testosterone Oral isotretinoin and topical steroid (2 cases)
Systemic corticosteroid (1 case)
 Weimann and Bohles, 19993 M 1 13 Hereditary tall stature treated with high dose of testosterone Testosterone 250 mg once a wk over 6 mo Isotretinoin therapy (0.3 mg/kg/d), methylprednisolone and cefaclor