Table 1.
Bactericidal activities of Mul-1867 and other antibacterials against non-mucoid P. aeruginosa isolates
Antibacterials | Susceptibility breakpoint (µg/mL) | P. aeruginosa strain minimal inhibitory concentration (µg/mL) | |||
---|---|---|---|---|---|
AGR14 | MR 45 | VT-VAP-72 | ATCC 27853 | ||
Mul-1867 | NDa | 8 | 8 | 4 | 1 |
Amikacin | ≤16 | 128 | 256 | 128 | 4 |
Aztreonam | ≤8 | 32 | 128 | 64 | 2 |
Ceftazidime | ≤8 | 32 | 32 | 16 | 2 |
Meropenem | ≤2 | 32 | 64 | 32 | 1 |
Piperacillin | ≤16 | >256 | 256 | 128 | 4 |
Tobramycin | ≤4 | 32 | 32 | 32 | 1 |
a ND no data