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. 2016 Mar 22;7:45. doi: 10.1186/s13287-016-0306-3

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© Webb et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — A small LMW screen designed to identify Scx upregulators using high-content imaging a. Human TSCs lose nuclear Scx nuclear localization with passages b, c. Hits were identified as strong Scx inducers by displaying higher levels compared with our positive control, TGFβ2 d, e. LMW low molecular weight, Scx scleraxis, TGFβ2 transforming growth factor beta-2, TSC tendon stem cell