Table 2.

Distributions of genotype and allele frequency in healthy controls and patients

SNP	Genotype	Healthy controls (n = 253)	T2D patients (n = 234)	CAD patients (n = 200)	T2D &CAD patients (n = 185)	HWEa	p valueb	Additive model, p valuec	Dominant model, p valuec
rs174537G>T	GG	65	88	58	63	0.56	0.009	0.032	0.027
	GT	131	106	90	91
	TT	57	40	52	31
rs174616C>T	CC	113	104	88	99	0.59	0.383	0.445	0.180
	TC	115	109	90	68
	TT	25	21	22	18
rs174460C>T	TT	151	129	106	112	0.56	0.185	0.136	0.344
	TC	91	81	78	56
	CC	11	24	16	17
rs174450A>C	AA	101	86	82	80	0.46	0.550	0.743	0.589
	AC	122	113	96	80
	CC	30	35	22	25

^aHardy–Weinberg Equilibrium (HWE) was calculated in healthy controls

^b p values derived from the Chi square test of allele frequency

^c p values derived from the Chi square test of genotype distribution