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. 2016 Mar 22;13:9. doi: 10.1186/s12979-016-0063-2

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© Vianello et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Circulating levels of molecules involved into endothelium remodeling in aortic dissection and controls patients. AAD patients have higher level of CD40L, MPO, TIMP-1, and MMP-1 than controls (p < 0.05). The same trend was also highlighted subdividing AAD patients in type A and B according to Stanford classification (p < 0.05). No statistically significance was observed in MMP-2 and MMP-9 circulating levels between AAD and control patients. Between A and B subgroups of ADD patients any statistically significance was observed (p = 0.05)