Table 1.

Details of MPP7 SNPs associated with POAG in Indian population

SNP ID	Minor allele	Discovery cohort (347 cases/354 controls)			Validation cohort (319 cases/297 controls)			Meta-analysis (666 cases/651 controls)
		MAF (Cases/Controls)	plogistic	OR (95 % CI)	MAF (Cases/Controls)	P	OR (95 % CI)	Pmeta
rs7916852	C	0.54/0.43	9.19x10−4	1.54 (1.25-1.9)	0.61/0.5	1.71x10−4	1.54 (1.23-1.93)	5.7x10−7
rs10763644	G	0.54/0.44	1.24x10−3	1.53 (1.23-1.89)	0.61/0.5	1.33x10−3	1.55 (1.24-1.95)	6.18x10−7
rs10763643	A	0.48/0.4	0.018	1.4 (1.13-1.72)	0.58/0.44	3.35x10−6	1.7 (1.36-2.14)	7.46x10−7
rs4749305	A	0.48/0.4	0.020	1.39 (1.12-1.71)	0.55/0.44	8.42x10−5	1.57 (1.25-1.96)	9.92x10−6
rs11006851	G	0.48/0.4	0.023	1.39 (1.13-1.72)	0.55/0.44	1.26x10−4	1.55 (1.24-1.94)	1.57x10−5
rs10763642	A	0.4/0.49	1.9x10−3	0.69 (0.56-0.85)	0.34/0.42	3.51x10−3	0.71 (0.56-0.89)	2.03x10−5
rs10047289	A	0.4/0.49	3.9x10−3	0.71 (0.57-0.87)	0.34/0.43	2.44x10−3	0.7 (0.56-0.88)	2.92x10−5
rs7474568	A	0.46/0.36	1.82x10−3	1.52 (1.23-1.88)	0.5/0.43	5.42x10−3	1.38 (1.1-1.72)	3.03x10−5
rs4749301	A	0.46/0.36	1.8x10−3	1.52 (1.23-1.88)	0.5/0.42	5.42x10−3	1.38 (1.1-1.72)	3.03x10−5
rs3802520	A	0.36/0.45	6.7x10−3	0.7 (0.56-0.87)	0.33/0.4	9x10−3	0.73 (0.58-0.93)	1.68x10−4
rs7086023	A	0.4/0.33	0.040	1.36 (1.09-1.69)	0.45/0.36	1.78x10−3	1.44 (1.15-1.81)	2.58x10−4
rs12253376	A	0.32/0.41	0.017	0.7 (0.56-0.87)	0.31/0.37	0.025	0.76 (0.6-0.97)	1x10−3
rs3885634	G	0.33/0.41	0.020	0.71 (0.57-0.89)	0.31/0.37	0.021	0.76 (0.6-0.96)	1.11x10−3
rs11006830	G	0.33/0.41	0.022	0.72 (0.58-0.89)	0.31/0.37	0.035	0.78 (0.61-0.98)	1.88x10−3

Note: P_logistic refers to the p-value calculated by logistic regression analysis and P of validation phase refers to chi-square p-value. P_meta refers to the meta-analysis of P_logistic of discovery phase (see Additional file 2) and P of the validation phase