Table 7.
Comparison of adverse perinatal outcomes in pregnant women with and without metabolic syndrome according to four definitions
| Adverse perinatal outcome | Entire study group (N = 675) | NCEP ATP III [5] | p value | JIS MetS Criteria [6] | p value | NCEP ATP III (Bartha [10]) | p value | NHLBI/AHA (Chatzi [8, 9] | p value | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| With MetS N = 197 |
Without MetS N = 478 |
With MetS N = 247 |
Without MetS N = 428 |
With MetS N = 12 | Without MetS N = 663 |
With MetS N = 85 | Without MetS N = 590 |
||||||
| Visible malformation (%) | 1 | 1 (0.5) | 0 (0.0) | 0.6468 | 0 (0) | 1 (0.2) | 1.0 | 0 (0.0) | 1 (0.2) | 1.0 | 0 (0.0) | 1 (0.01) | 1.0 |
| Icterus (%) | 4 | 2 (0.1) | 2 (0.4) | 0.7137 | 2 (0.8) | 2 (0.5) | 0.9699 | 0 (0.0) | 4 (0.6) | 1.0 | 1 (1.2) | 3 (0.05) | 1.0 |
| Macrossomia | 28 | 14 (7.1) | 14 (2.9) | 0.236 | 15 (6.0) | 13 (3.0) | 0.0882 | 2 (16.7) | 26 (3.9) | 0.1432 | 6 (7.0) | 22 (3.7) | 0.2507 |
| Prematurity (%) | 26 | 7 (3.5) | 19 (3.9) | 0.9691 | 9 (3.6) | 17 (4.0) | 0.9953 | 1 | 25 (3.7) | 0.9544 | 5 (5.9) | 21 (3.5) | 0.4599 |
| Respiratory Distress Syndrome (%) | 14 | 3 (1.5) | 11 (2.3) | 0.7278 | 3 (1.2) | 11 (2.6) | 0.3628 | 0 (0.0) | 14 (2.1) | 1.0 | 2 (2.3) | 12 (2.0) | 1.0 |
| Stillbirth (%) | 15 | 6 (3.0) | 9 (1.9) | 0.5192 | 6 (2.4) | 9 (2.1) | 0.9952 | 2 (16.7) | 13 (2.0) | 0.0148 | 3 (3.5) | 12 (2.0) | 0.6305 |
| Apgar score <7 | |||||||||||||
| 1 min (%) | 31 | 6 (3.0) | 25 (5.2) | 0.3028 | 9 (3.6) | 22 (5.1) | 0.4816 | 0 (0.0) | 31 (4.8) | 0.9433 | 4 (4.7) | 27 (4.6) | 1.0 |
| 5 min (%) | 10 | 3 (1.5) | 7 (1.5) | 1.0 | 3 (1.2) | 7 (1.6) | 0.9161 | 10 (1.5) | 1.0 | 1 (1.2) | 9 (1.5) | 1.0 | |
| Number of newborns with APO | 95 | 30 (15.2) (a) | 65 (13.6) | 0.6658 | 36 (14.6) (a) | 59 (13.8) | 0.8655 | 4 (33.3) (a) | 91 (13.7) | 0.1293 | 15 (17.6) (a) | 80 (13.5) | 0.3973 |
| Any adverse perinatal outcome APO N (%) | 129 | 42 (21.3) (a) |
87 (12.2) | 0.4069 | 47 (19.0) (a) |
82 (19.2) | 1.000 | 5 (41.7) (a) | 124 (18.7) | 0.1021 | 22 (25.9) (a) | 106 (18.0) | 0.1112 |
* Difference test of proportions of number of newborns with APO p = 0.3435 (aaa and a). * Difference test of proportions of any adverse perinatal outcomes is p = 0.1898