Table 1.

Key similarities and divergences between the HAS and NICE methodological guidelines and processes for economic valuation of health interventions

HAS and NICE guidelines similarities	HAS and NICE guidelines divergences
CUA preferred analytical framework Subpopulations identification and analyses Comparators to take into consideration Time horizon Source of data for health effects of interventions Consideration of every positive and negative effect Effectiveness preferred over efficacy Sensitivity analyses	Possibility of a CEA (incremental cost per life-year gained) as base case in France Existence of cost-effectiveness thresholds Study population Quality of life valuation methods Perspective on costs Types of resources considered Valuation of the resources used Discounting Decision impacted by recommendation Place of the recommendation in the decision process

CUA: cost-utility analysis; CEA: cost-effectiveness assessment.