Table 1.
ELDA analysis of TIC frequency at day 51 post-transplant for the CD49fNeg/CD24Low or CD49f+/CD24High sorted cell populations isolated from MMTV-PyMT+ tumors that were implanted into the cleared mammary fat pad of recipient mice at low density; the number of animals producing tumors/the number of animals transplanted is also indicated
| Sorted population: | |||
|---|---|---|---|
| Number of cells injected: | CD49fNeg/CD24Low | CD49f+/CD24High | p-value: |
| 200 | 2/7 (29 %) | 5/7 (71 %) | |
| 100 | 1/6 (17 %) | 4/6 (67 %) | |
| 50 | 1/8 (12 %) | 6/9 (67 %) | |
| 25 | 0/8 (0 %) | 1/8 (12 %) | |
| Estimated TIC Frequency | 1/578 | 1/99 | |
| (95 % C.I.) | (1/216 to 1/1,544) | (1/58 to 1/170) | 0.00043 |