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. 2016 Jan 19;8(6):e1082691. doi: 10.1080/19420889.2015.1082691

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© 2015 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 1. — Phylogenetic reconstruction of the PIPK family of phosphoinositide kinases. Taxa are colored by eukaryotic super-group according to the key. Unsupported branches are gray; support levels are indicated with discs according to the key. The topology shown is the best scoring ML topology (RaxML). A well-supported clade containing characterized PIPK3 gene products is found across the eukaryotes. The remaining sequences group according to eukaryotic super-group suggesting multiple, independent instances of gene duplication following divergence of the eukaryotic lineages.