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. 2015 Nov 13;6(5):91–101. doi: 10.1080/21541264.2015.1114983

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© 2015 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 5. — Genome-wide RNAPII and CTD K7me_1/2 methylation profiles. (A) Diagram summarizing the average transcription unit with representative clusters for RNAPII and CTD K7me1/2 occupancy profiles of top 5%, 20%, 20–80% of signals across the genome using average transcription unit analysis (see Methods). (B) Distribution of RNAPII upstream and downstream of TSS for the top 20% of genes >4kb. (C) Examples of gene RPL22L1 (Ribosomal Protein L22-like-1), IER5 (immediate early response 5) and EIF1B (eukaryotic translation initiation factor 1B) showing RNAPII distribution and signals for Tyr1P, Ser7P, Ser5P, Ser2P, and CTD Kme1/2. Strand (+) shows genes in 5' – 3′ and strand ( − ) in 3′ − 5' orientation.