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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Dev Dyn. 2016 Jan 4;245(3):190–196. doi: 10.1002/dvdy.24374

Fig. 4.

Fig. 4

Cell polarization in the FNP. (A) Measurements of the angle formed by a line connecting both the center of the Golgi (red) and the nucleus (orange) relative to a reference line (dashed arrow) have shown that mesenchymal cells in the FNP are oriented toward the direction of growth (dashed line) (Li et al. 2013). (B) Ectopic expression of fgf8 in the FNP (cells with blue nuclei), induced by injection of RCAS::Fgf8, disrupts this polarity, suggesting that a morphogenetic gradient of FGF8 (blue shading) emanating from the epithelium surrounding the nasal pits is involved in polarization of the mesenchyme in the FNP (Li et al. 2013).