Skip to main content
. Author manuscript; available in PMC: 2016 Mar 22.
Published in final edited form as: JACC Cardiovasc Imaging. 2009 Jan;2(1):97–113. doi: 10.1016/j.jcmg.2008.11.001

Figure 1. In Vivo Multichannel NIRF Imaging of Plaque Macrophages and Osteogenesis in Aged ApoE −/− Mice.

Figure 1

(A) Calcified carotid artery atherosclerotic plaque gross morphology correlated with intravital fluorescence microscopy images of macrophages (green) and calcification (red). Merged intravital microscopy images reveal no colocalization between macrophages and calcification (bar = 500 µm). (B) Cross-sectional fluorescence microscopy with image overlay revealed a similar spatially distinct relationship (bar = 200 µm). Reprinted, with permission, from Aikawa et al. (3). ApoE−/−= apolipoprotein deficient; NIRF = near-infrared fluorescence.