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. 2016 Mar 22;11:31. doi: 10.1186/s13000-016-0481-7

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© Reggiani Bonetti et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Grades of malignancy of CRC based on the highest PDC count. a PDC G1: <5 clusters [H&E stain 10×]. The particular of the clusters showing more than 5 undifferentiated cancer cells [asterisk - H&E stain 20×]. b PDC G2: 5–9 clusters [H&E stain 20×]. c PDC G3: ≥ 10 clusters at the fron of the tumor mass [H&E stain 10×]. d PDC G3: The same clusters at major resolution [H&E stain; 20×]