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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Pharm Res. 2014 Nov 7;32(5):1615–1625. doi: 10.1007/s11095-014-1561-6

Fig. 6.

Fig. 6

CNA-IONP cell association/uptake and CNA-IONP and Lucifer yellow flux across MDCKII cells. CNA-IONP MDCKII cell association/uptake after 37°C for 6 h (n=3), conventional hyperthermia at 43°C (0.5 h) followed by 37°C for 6 h (n=3), or AMF-induced hyperthermia (0.5 h) followed by 37°C for 6 h (n=4) (a). CNA-IONP flux across a MDCKII in vitro BBB model (b). The effect of conventional and AMF-induced hyperthermia on LY flux across MDCKII cells after 43°C incubation (n=3) or AMF for 0.5 h followed by 37°C for 6 h (n=4), compared to 37°C control (n=3) (c). * Significantly different compared to AMF (0.5 h) in panel A or compared to 37°C and conventional hyperthermia in panels B and C.