Figure 1.
A. Quantification of GAD67 mRNA hybridization signal demonstrates increased levels in the dentate gyrus granule cell layer of Poly I:C (maternal immune activation) animals at P60. B. Quantification of GAD67 mRNA labeling in the CA2 region of the hippocampus revealed decreased expression at P30 and, in contrast, increased expression at P60 in Poly I:C offspring. C. Measurement of GAD67 mRNA expression in the thalamic reticular nucleus revealed an increase in hybridization signal at P60. D. Decreased cRNA-labeling for GAD67 mRNA was found in the prelimbic region of the medial prefrontal cortex of Poly I:C-treated animals at P60. Data are expressed as mean ± SEM. *p < 0.05, ** p < 0.01 compared to respective control values.