Table 3.

Serum Androstenedione and Testosterone After Single Doses of NBI-77860, Mean, and Percent Change From Placebo During the Morning Window (6–10 am)

Participant	Dose	Androstenedione		Testosterone
		Mean (ng/dl)	% Change From Placebo	Mean (ng/dl)	% Change From Placebo
1011001	Placebo	303.0	0	105.3	0
	300	295.3	−2.5	131.7	25.0
	600	265.7	−12.3	122.7	16.5
1011002	Placebo	185.3	0	49.7	0
	300	190.7	2.9	42.7	−14.1
	600	78.0	−57.9	23.0	−53.7
1011003	Placebo	146.0	0	35.0	0
	300	132.7	−9.1	32.3	−7.6
	600	147.7	1.1	34.0	−2.9
1011004	Placebo	820.0	0	169.3	0
	300	747.7	−8.8	158.7	−6.3
	600	934.0	13.9	164.0	−3.1
1011005	Placebo	308.0	0	76.3	0
	300	377.0	22.4	107.3	40.6
	600	420.3	36.5	83.0	8.7
1011006	Placebo	195.7	0	59.7	0
	300	141.0	−27.9	36.7	−38.5
	600	173.3	−11.4	50.7	−15.1
1011007	Placebo	145.3	0	47.3	0
	300	135.3	−6.9	32.3	−31.7
	600	84.7	−41.7	19.0	−59.9
1011008	Placebo	914.0	0	127.0	0
	300	973.3	6.5	147.3	16.0
	600	1366.3	49.5	194.3	53.0