Table 2.

Adjusted Rates in Preclinical Outcomes per Initiated Cycle According to Urinary BPA Concentrations by Soy Intake Among 239 Women (Contributing to 347 Fresh Cycles) From the EARTH Study

	MII Oocyte Yield		Total Oocyte Yield		Proportion With >1 Best Embryo Qualitya		Fertilization Rate, All Cycles
	No Soy Intake	Soy Intake	No Soy Intake	Soy Intake	No Soy Intake	Soy Intake	No Soy Intake	Soy Intake
Urinary BPA, μg/L
<LOD 0.96	9.58 (7.74–11.85)	8.90 (7.90–10.01)	11.46 (9.26–14.19)	10.33 (9.21–11.61)	0.33 (0.14–0.60)	0.41 (0.29–0.55)	0.74 (0.64, 0.83)	0.72 (0.67, 0.77)
0.97–1.41	8.06 (6.29–10.33)	9.0 (8.03–10.07)	10.42 (8.19–13.27)	10.77 (9.64–12.03)	0.46 (0.20–0.74)	0.47 (0.35–0.60)	0.72 (0.59, 0.82)	0.71 (0.66, 0.76)
1.42–2.25	8.70 (7.21–10.48)	10.41 (9.24–11.73)	10.02 (8.30–12.10)	11.69 (10.38–13.15)	0.41 (0.22–0.63)	0.44 (0.31–0.58)	0.60 (0.50, 0.69)	0.76 (0.71, 0.81)
2.28–16.55	9.18 (7.37–11.42)	7.97 (7.03–9.03)	11.16 (8.96–13.92)	9.49 (8.39–10.72)	0.37 (0.17–0.63)	0.46 (0.33–0.60)	0.72 (0.61, 0.81)	0.74 (0.68, 0.79)
P for trendb	0.77	0.12	0.91	0.40	0.55	0.61	0.92	0.54
P for interaction	0.36	0.58			0.85		0.10

Data are presented as rates (95% CI) adjusted for age (continuous), BMI (continuous), races (white, black, Asian, and others), and infertility diagnosis (male, female, and unexplained). A total of 100 fresh cycles were carried out among women who did not consume soy and 247 fresh cycles among women who consumed soy.

^aWe classified embryos as best quality if they had 4 cells on day 2, 8 cells on day 3, and a morphologic quality score of 1 or 2 on days 2 and 3.

^bTests for trend were performed using the median level of urinary BPA level in each group as a continuous variable in the model.