Table 4. Factors associated with moderate liver fibrosis (F ≥ 2).

Factor	Category	Fibrosis stage	Univariate analysis			Multivariate analysis
			OR	95% CI	P value	OR	95% CI	P value
Fuc-Hpt, U/mL	≤ 559 (median), > 559	F0-1 vs. F2-4	3.26	2.06–5.16	< 0.05	1.28	0.71–2.28	0.41
Mac-2 bp, ng/mL	≤ 1847 (median), > 1847	F0-1 vs. F2-4	4.44	2.77–7.12	< 0.05	2.23	1.27–3.92	< 0.05
Liver histology, activity	A0-1, A2-3	F0-1 vs. F2-4	2.08	1.32–3.27	< 0.05	1.38	0.80–2.36	0.25
FIB4 index	< 2.67, ≥ 2.67	F0-1 vs. F2-4	6.14	3.74–10.1	< 0.05	3.19	1.81–5.68	< 0.05
PT, %	≥ 80, < 80	F0-1 vs. F2-4	2.89	1.54–5.42	< 0.05	1.48	0.68–3.27	0.32
Alb, g/dL	≥ 4.0, < 4.0	F0-1 vs. F2-4	2.43	1.52–3.91	< 0.05	0.82	0.50–1.71	0.82
AFP, ng/mL	< 10, ≥ 10	F0-1 vs. F2-4	8.18	4.35–15.4	< 0.05	3.13	1.52–6.67	< 0.05

OR: odds ratio.