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. 2016 Mar 22;11(3):e0150472. doi: 10.1371/journal.pone.0150472

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© 2016 Kumar et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 3 — Morphological analysis of the inner ears using the whole mount clearing method showed abnormal superior semi-circular canal formation in the homozygous mutants of line Pou3f3^L423P. Left picture shows a control inner ear with normal semi-circular canals. Right picture shows the smaller inner ear of a Pou3f3^L423P homozygous mutant animal with abnormal superior semi-circular canal formation. Red arrow shows the constriction of the superior semi-circular canal. SSCC: superior semi-circular canal, PSCC: posterior semi-circular canal, ASCC: anterior semi-circular canal.