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. 2016 Mar 22;11(3):e0151805. doi: 10.1371/journal.pone.0151805

Table 1. Univariate analysis for risk factors of MIOR.

Factors All (n = 538), Mean ±SD, n (%) or Median (range) MIOR
No (n = 470), Mean ±SD, n (%) or Median (range) Yes (n = 68), Mean ±SD, n (%) or Median (range) P
Age (year) 55.39±13.71 55.42±13.45 55.18±15.51 0.904
Preoperative GCS* 15 (3–15) 15 (3–15) 13 (3–15) 0.002
Sex 1.000
 Women 337(63%) 294(63%) 43(63%)
 Men 201(37%) 176(37%) 25(37%)
Surgical experience 0.009
 Experienced 225(42%) 207(44%) 18(26%)
 Inexperienced 313(58%) 263(56%) 50(74%)
Aneurysm location 0.057
 ICA 238(44%) 207(44%) 31(46%)
 MCA 96(18%) 79(17%) 17(25%)
 ACA 175(33%) 155(33%) 20(29%)
 Posterior circulation 29(5%) 29(6%) 0(0%)
Aneurysm size 0.453
 <15 mm 469(87%) 412(88%) 57(84%)
 15–25 mm 49(9%) 42(9%) 7(10%)
 >25 mm 20(4%) 16(3%) 4(6%)
Lobulated aneurysm 0.165
 No 330(61%) 294(63%) 36(53%)
 Yes 208(39%) 176(37%) 32(47%)
Ruptured aneurysm 0.044
 No 79(15%) 75(16%) 4(6%)
 Yes 459(85%) 395(84%) 64(94%)

ACA: anterior cerebral artery, GCS: Glasgow Coma Scale, ICA: internal carotid artery, MCA: middle cerebral artery, MIOR: major intraoperative rupture, SD: standard deviation.

*Median (range) and using Mann-Whitney U-test